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CITRULLINE

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FERMENTEDL-CITRULLINE

L–Citrulline is an amino acid that has been found to play an important role in nitric oxide (NO) metabolism and regulation. L-Citrulline is converted to L-Arginine in the body, leading to increases in both L-Arginine and nitric oxide. Increased production of nitric oxide promotes vascular dilation, which helps support normal oxygen and blood circulation.

NOTHING COMES CLOSE

PHARMACOKINETIC ADVANTAGES OF L-CITRULLINE

The pharmacokinetic advantage of L-Citrulline is that it is not subject to any elimination by the liver prior to entering the bloodstream. Conversely, L-Arginine is subject to extensive elimination by the gut wall and liver. The majority of L-Citrulline is converted to L-Arginine in the kidney. (1) Once in circulation, L-Arginine is readily converted into L-Citrulline and nitric oxide, which in turn serves as an L-Arginine precursor (see figure below).

Conversion from L-Arginine to L-Citrulline

Absorption of L-Arginine & L-Citrulline

*Citrulline ingestion enables effective supply of arginine.

ROLES OF CITRULLINE IN THE BODY

  • Converts to arginine and nitric oxide
  • Supports nutrient delivery via vascular blood flow

HOW DOES PURE L-CITRULLINE COMPARE TO L-CITRULLINE MALATE?

L-Citrulline Malate is mixed 1:1 (Malic Acid + L-Citrulline). Basically, the L-Citrulline is cut in half! Most brands use L-Citrulline Malate 1:1 ratio due to cost (cheap!) – about 50% less per kilogram than Pure L-Citrulline.

BENEFITS OF KAGED MUSCLE® L-CITRULLINE

  • Fermentation derived versus synthetic
  • GRAS

DID YOU KNOW?

Most L-Citrulline on the market today is made from duck feathers and human hair—not ours!

BETTER TOGETHER

 

Combining Kaged Muscle’s L-Citrulline with BCAAs is the perfection combination to help achieve your fitness goals.

REFERENCES

1. Curis, E. et al., Amino acids. 29(3):177-205, 2005 modified

 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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